RETRACTED ARTICLE: Hypoxia-induced autophagy of stellate cells inhibits expression and secretion of lumican into microenvironment of pancreatic ductal adenocarcinoma

Lumican is secreted by pancreatic stellate cells and inhibits cancer progression. Extracellular lumican inhibits cancer cell replication and restrains growth of early-stage pancreatic adenocarcinoma (PDAC) such that patients with tumors containing stromal lumican experience a three-fold longer survi...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Li, Xinqun, Lee, Yeonju, Kang, Ya’an, Dai, Bingbing, Perez, Mayrim Rios, Pratt, Michael, Koay, Eugene J., Kim, Michael, Brekken, Rolf A., Fleming, Jason B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329841/
https://ncbi.nlm.nih.gov/pubmed/30283082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0207-3
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