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NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by the selective loss of dopaminergic neurons in substantia nigra pars compacta (SNpc). Although the pathogenic mechanism underlying PD remains largely unknown, decreased nigral glutathione (GSH) in postmorte...

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Podrobná bibliografie
Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Zhou, Jing-si, Zhu, Zhou, Wu, Feng, Zhou, Ying, Sheng, Rui, Wu, Jun-chao, Qin, Zheng-hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329815/
https://ncbi.nlm.nih.gov/pubmed/29769744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0003-0
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