NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation

Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by the selective loss of dopaminergic neurons in substantia nigra pars compacta (SNpc). Although the pathogenic mechanism underlying PD remains largely unknown, decreased nigral glutathione (GSH) in postmorte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Pharmacol Sin
Prif Awduron: Zhou, Jing-si, Zhu, Zhou, Wu, Feng, Zhou, Ying, Sheng, Rui, Wu, Jun-chao, Qin, Zheng-hong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329815/
https://ncbi.nlm.nih.gov/pubmed/29769744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0003-0
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