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Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures

Understanding how forces orchestrate tissue formation requires technologies to map internal tissue stress at cellular length scales. Here, we develop ultrasoft mechanosensors that visibly deform under less than 10 Pascals of cell-generated stress. By incorporating these mechanosensors into multicell...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lee, Wontae, Kalashnikov, Nikita, Mok, Stephanie, Halaoui, Ruba, Kuzmin, Elena, Putnam, Andrew J., Takayama, Shuichi, Park, Morag, McCaffrey, Luke, Zhao, Ruogang, Leask, Richard L., Moraes, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329783/
https://ncbi.nlm.nih.gov/pubmed/30635553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07967-4
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