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Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization
Efficient and site-specific chemical modification of proteins under physiological conditions remains a challenge. Here we report that 1,4-dinitroimidazoles are highly efficient bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. Under acidic to neutral aq...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329768/ https://ncbi.nlm.nih.gov/pubmed/30635561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08010-2 |
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