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Recombinant AAV-CEA Tumor Vaccine in Combination with an Immune Adjuvant Breaks Tolerance and Provides Protective Immunity

Carcinoembryonic antigen (CEA) is a human glycoprotein involved in cellular adhesion and expressed during human fetal development. Although expression of CEA largely ceases prior to birth, several human epithelial cancers, including colorectal, gastric, squamous esophageal, and breast carcinomas hav...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Hensel, Jonathan A., Khattar, Vinayak, Ashton, Reading, Ponnazhagan, Selvarangan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329706/
https://ncbi.nlm.nih.gov/pubmed/30666318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.12.004
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