Recombinant AAV-CEA Tumor Vaccine in Combination with an Immune Adjuvant Breaks Tolerance and Provides Protective Immunity

Carcinoembryonic antigen (CEA) is a human glycoprotein involved in cellular adhesion and expressed during human fetal development. Although expression of CEA largely ceases prior to birth, several human epithelial cancers, including colorectal, gastric, squamous esophageal, and breast carcinomas hav...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Oncolytics
Hauptverfasser: Hensel, Jonathan A., Khattar, Vinayak, Ashton, Reading, Ponnazhagan, Selvarangan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329706/
https://ncbi.nlm.nih.gov/pubmed/30666318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.12.004
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