Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses

PURPOSE: Saccharomyces cerevisiae, a nonpathogenic yeast, has previously been used as a vehicle to elicit immune responses to foreign antigens, and tumor-associated antigens, and has been shown to reduce tumorburden in mice. Studies were designed to determine if vaccination of human carcinoembryonic...

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Bibliografski detalji
Glavni autori: Wansley, Elizabeth K., Chakraborty, Mala, Hance, Kenneth W., Bernstein, Michael B., Boehm, Amanda L., Guo, Zhimin, Quick, Deborah, Franzusoff, Alex, Greiner, John W., Schlom, Jeffrey, Hodge, James W.
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740939/
https://ncbi.nlm.nih.gov/pubmed/18594015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0393
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