CDKN2B downregulation and other genetic characteristics in T-acute lymphoblastic leukemia

We identified principal genetic alterations in 97.1% (99/102) of patients with T-acute lymphoblastic leukemia (T-ALL) using integrative genetic analyses, including massive parallel sequencing and multiplex ligation-dependent probe amplification (MLPA). A total of 133 mutations were identified in the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Mol Med
Auteurs principaux: Jang, Woori, Park, Joonhong, Kwon, Ahlm, Choi, Hayoung, Kim, Jiyeon, Lee, Gun Dong, Han, Eunhee, Jekarl, Dong Wook, Chae, Hyojin, Han, Kyungja, Yoon, Jae-Ho, Lee, Seok, Chung, Nack-Gyun, Cho, Bin, Kim, Myungshin, Kim, Yonggoo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329696/
https://ncbi.nlm.nih.gov/pubmed/30635552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0195-x
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