Ubiquitin C decrement plays a pivotal role in replicative senescence of bone marrow mesenchymal stromal cells

Human bone marrow-mesenchymal stromal cells (hBM-MSCs) undergo cellular senescence during in vitro culture. In this study, we defined this replicative senescence as impaired proliferation, deterioration in representative cell characteristics, accumulated DNA damage, and decreased telomere length and...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kim, Jiyeon, Kim, Yonggoo, Choi, Hayoung, Kwon, Ahlm, Jekarl, Dong Wook, Lee, Seungok, Jang, Woori, Chae, Hyojin, Kim, Jung Rok, Kim, Jung Min, Kim, Myungshin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833785/
https://ncbi.nlm.nih.gov/pubmed/29382826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0032-5
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