Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells

Natural killer (NK) cells develop from common progenitors but diverge into distinct subsets, which differ in cytokine production, cytotoxicity, homing and memory traits. Given their promise in adoptive cell therapies for cancer, a deeper understanding of regulatory modules controlling clinically ben...

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Veröffentlicht in:Cell
Hauptverfasser: Collins, Patrick L., Cella, Marina, Porter, Sofia I., Li, Shasha, Gurewitz, Greer L., Hong, Henoch S., Johnson, R. Paul, Oltz, Eugene M., Colonna, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329660/
https://ncbi.nlm.nih.gov/pubmed/30595449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.045
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