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Life and cancer without telomerase: ALT and other strategies for making sure ends (don’t) meet

While most cancer cells rely on telomerase expression/re-activation for linear chromosome maintenance and sustained proliferation, a significant population of cancers (10–15%) employs telomerase independent strategies, collectively dubbed Alternative Lengthening of Telomeres (ALT). Most ALT cells re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Crit Rev Biochem Mol Biol
Egile Nagusiak: Apte, Manasi S., Cooper, Julia Promisel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329634/
https://ncbi.nlm.nih.gov/pubmed/27892716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2016.1260090
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