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Life and cancer without telomerase: ALT and other strategies for making sure ends (don’t) meet
While most cancer cells rely on telomerase expression/re-activation for linear chromosome maintenance and sustained proliferation, a significant population of cancers (10–15%) employs telomerase independent strategies, collectively dubbed Alternative Lengthening of Telomeres (ALT). Most ALT cells re...
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| Publicado no: | Crit Rev Biochem Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329634/ https://ncbi.nlm.nih.gov/pubmed/27892716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10409238.2016.1260090 |
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