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Regulation of heterologously expressed 5‐HT(1B) receptors coupling to potassium channels in AtT‐20 cells

BACKGROUND AND PURPOSE: 5‐HT(1B) receptors are widely expressed GPCRs and a target of triptans, the most commonly prescribed anti‐migraine drugs. There is very limited information about the acute, agonist‐induced regulation of 5‐HT(1B) receptor signalling and so we sought to characterize this in a n...

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Pubblicato in:Br J Pharmacol
Autori principali: Heblinski, Marika, Bladen, Christopher, Connor, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329624/
https://ncbi.nlm.nih.gov/pubmed/30447001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14547
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