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Isovaline Does Not Activate GABA(B) Receptor-Coupled Potassium Currents in GABA(B) Expressing AtT-20 Cells and Cultured Rat Hippocampal Neurons

Isovaline is a non-proteinogenic amino acid that has analgesic properties. R-isovaline is a proposed agonist of the γ-aminobutyric acid type B (GABA(B)) receptor in the thalamus and peripheral tissue. Interestingly, the responses to R-isovaline differ from those of the canonical GABA(B) receptor ago...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pitman, Kimberley A., Borgland, Stephanie L., MacLeod, Bernard, Puil, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337901/
https://ncbi.nlm.nih.gov/pubmed/25706125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118497
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