The flow responsive transcription factor Klf2 is required for myocardial wall integrity by modulating Fgf signaling

Complex interplay between cardiac tissues is crucial for their integrity. The flow responsive transcription factor KLF2, which is expressed in the endocardium, is vital for cardiovascular development but its exact role remains to be defined. To this end, we mutated both klf2 paralogues in zebrafish,...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Rasouli, Seyed Javad, El-Brolosy, Mohamed, Tsedeke, Ayele Taddese, Bensimon-Brito, Anabela, Ghanbari, Parisa, Maischein, Hans-Martin, Kuenne, Carsten, Stainier, Didier Y
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2018
Konular:
Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329608/
https://ncbi.nlm.nih.gov/pubmed/30592462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38889
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