The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and escaping to the cytosol. To prevent the leakage of pathogen virulence and host defence factors, as well as bacteria escape, host cells have to...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: López-Jiménez, Ana T., Cardenal-Muñoz, Elena, Leuba, Florence, Gerstenmaier, Lilli, Barisch, Caroline, Hagedorn, Monica, King, Jason S., Soldati, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329560/
https://ncbi.nlm.nih.gov/pubmed/30596802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007501
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