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The ESCRT and autophagy machineries cooperate to repair ESX-1-dependent damage at the Mycobacterium-containing vacuole but have opposite impact on containing the infection

Phagocytic cells capture and kill most invader microbes within the bactericidal phagosome, but some pathogens subvert killing by damaging the compartment and escaping to the cytosol. To prevent the leakage of pathogen virulence and host defence factors, as well as bacteria escape, host cells have to...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Pathog
Κύριοι συγγραφείς: López-Jiménez, Ana T., Cardenal-Muñoz, Elena, Leuba, Florence, Gerstenmaier, Lilli, Barisch, Caroline, Hagedorn, Monica, King, Jason S., Soldati, Thierry
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329560/
https://ncbi.nlm.nih.gov/pubmed/30596802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007501
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