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Chemogenomic model identifies synergistic drug combinations robust to the pathogen microenvironment
Antibiotics need to be effective in diverse environments in vivo. However, the pathogen microenvironment can have a significant impact on antibiotic potency. Further, antibiotics are increasingly used in combinations to combat resistance, yet, the effect of microenvironments on drug-combination effi...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6329523/ https://ncbi.nlm.nih.gov/pubmed/30596642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006677 |
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