Buprenorphine Maintenance Subjects Are Hyperalgesic and Have No Antinociceptive Response to a Very High Morphine Dose

OBJECTIVE: Acute pain management in opioid-dependent persons is complicated because of tolerance and opioid-induced hyperalgesia. Very high doses of morphine are ineffective in overcoming opioid-induced hyperalgesia and providing antinociception to methadone-maintained patients in an experimental se...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pain Med
Egile Nagusiak: Athanasos, Peter, Ling, Walter, Bochner, Felix, White, Jason M, Somogyi, Andrew A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
OPIOIDS & SUBSTANCE USE DISORDERS SECTION
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329438/
https://ncbi.nlm.nih.gov/pubmed/29514333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pm/pny025
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