The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma

Background: Little is known about the prognostic significance of somatically mutated genes in metastatic melanoma (MM). We have employed a combined clinical and bioinformatics approach on tumor samples from cutaneous melanoma (SKCM) as part of The Cancer Genome Atlas project (TCGA) to identify mutat...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhao, Xiaobei, Little, Paul, Hoyle, Alan P., Pegna, Guillaume J., Hayward, Michele C., Ivanova, Anastasia, Parker, Joel S., Marron, David L., Soloway, Matthew G., Jo, Heejoon, Salazar, Ashley H., Papakonstantinou, Michael P., Bouchard, Deeanna M., Jefferys, Stuart R., Hoadley, Katherine A., Ollila, David W., Frank, Jill S., Thomas, Nancy E., Googe, Paul B., Ezzell, Ashley J., Collichio, Frances A., Lee, Carrie B., Earp, H. Shelton, Sharpless, Norman E., Hugo, Willy, Wilmott, James S., Quek, Camelia, Waddell, Nicola, Johansson, Peter A., Thompson, John F., Hayward, Nicholas K., Mann, Graham J., Lo, Roger S., Johnson, Douglas B., Scolyer, Richard A., Hayes, D. Neil, Moschos, Stergios J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329304/
https://ncbi.nlm.nih.gov/pubmed/30662871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00584
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