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Correlate tumor mutation burden with immune signatures in human cancers

BACKGROUND: Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have revealed that high TMB may yield many neoantigens to incite antitumor immune response, a systematic exploration of the correlation between TMB and...

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Veröffentlicht in:BMC Immunol
Hauptverfasser: Wang, Xiaosheng, Li, Mengyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329192/
https://ncbi.nlm.nih.gov/pubmed/30634925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0285-5
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