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Correlate tumor mutation burden with immune signatures in human cancers

BACKGROUND: Tumor mutation burden (TMB) has been associated with cancer immunotherapeutic response and cancer prognosis. Although many explorations have revealed that high TMB may yield many neoantigens to incite antitumor immune response, a systematic exploration of the correlation between TMB and...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Wang, Xiaosheng, Li, Mengyuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329192/
https://ncbi.nlm.nih.gov/pubmed/30634925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0285-5
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