Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency

BACKGROUND: Mouse somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors known to regulate pluripotency, including Oct4, Sox2, Klf4, and c-Myc. It has been reported that Sirtuin 6 (Sirt6), a member of the sirtuin family of NAD(+)-dependent protein deacetylas...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Stem Cell Res Ther
Main Authors: Xu, Peng, Wang, Ting-ting, Liu, Xiu-zhen, Wang, Nan-Yu, Sun, Li-hong, Zhang, Zhu-qin, Chen, Hou-zao, Lv, Xiang, Huang, Yue, Liu, De-Pei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329104/
https://ncbi.nlm.nih.gov/pubmed/30630525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1109-5
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