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Increased Ripk1-mediated bone marrow necroptosis leads to myelodysplasia and bone marrow failure in mice

Hematopoiesis is a dynamic system that requires balanced cell division, differentiation, and death. The 2 major modes of programmed cell death, apoptosis and necroptosis, share molecular machinery but diverge in outcome with important implications for the microenvironment; apoptotic cells are remove...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Wagner, Patrice N., Shi, Qiong, Salisbury-Ruf, Christi T., Zou, Jing, Savona, Michael R., Fedoriw, Yuri, Zinkel, Sandra S.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328629/
https://ncbi.nlm.nih.gov/pubmed/30413413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-05-847335
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