Blocking Thrombin Significantly Ameliorates Experimental Autoimmune Neuritis

Thrombin and its protease-activated receptor 1 (PAR1) are potentially important in peripheral nerve inflammatory diseases. We studied the role of thrombin and PAR1 in rat experimental autoimmune neuritis (EAN), a model of the human Guillain-Barré syndrome (GBS). EAN was induced by bovine peripheral...

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Bibliographic Details
Published in:Front Neurol
Main Authors: Shavit-Stein, Efrat, Aronovich, Ramona, Sylantiev, Constantin, Gera, Orna, Gofrit, Shany G., Chapman, Joab, Dori, Amir
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Neurology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328627/
https://ncbi.nlm.nih.gov/pubmed/30662428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.01139
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