Upregulated osterix promotes invasion and bone metastasis and predicts for a poor prognosis in breast cancer

Approximately 70% of patients with advanced breast cancer develop bone metastases, accompanied by complications, such as bone pain, fracture, and hypercalcemia. However, our understanding of the molecular mechanisms that govern this process remains fragmentary. Osterix (Osx) is a zinc finger-contain...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Yao, Bing, Wang, Jue, Qu, Shuang, Liu, Yang, Jin, Yuci, Lu, Jianlei, Bao, Qianyi, Li, Lingyun, Yuan, Hongyan, Ma, Changyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328543/
https://ncbi.nlm.nih.gov/pubmed/30631043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1269-3
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