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Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation

Osterix (Osx) is an essential transcription factor involved in osteoblast differentiation and bone formation. The precise molecular mechanisms of the regulation of Osx expression are not fully understood. In the present study, we found that in cells, both endogenous and exogenous Osx protein increas...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Lu, Jianlei, Qu, Shuang, Yao, Bing, Xu, Yuexin, Jin, Yucui, Shi, Kaikai, Shui, Yifang, Pan, Shiyang, Chen, Li, Ma, Changyan
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122325/
https://ncbi.nlm.nih.gov/pubmed/27250035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9650
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