Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation

Osterix (Osx) is an essential transcription factor involved in osteoblast differentiation and bone formation. The precise molecular mechanisms of the regulation of Osx expression are not fully understood. In the present study, we found that in cells, both endogenous and exogenous Osx protein increas...

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Vydáno v:Oncotarget
Hlavní autoři: Lu, Jianlei, Qu, Shuang, Yao, Bing, Xu, Yuexin, Jin, Yucui, Shi, Kaikai, Shui, Yifang, Pan, Shiyang, Chen, Li, Ma, Changyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper: Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122325/
https://ncbi.nlm.nih.gov/pubmed/27250035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9650
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