Activation of Human CD11b(+) B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease

B-cells mediate humoral adaptive immune response via the production of antibodies and cytokines, and by inducing T-cell activation. These functions can be attributed to distinct B-cell subpopulations. Infection with Trypanosoma cruzi, the causative agent of Chagas disease, induces a polyclonal B-cel...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Passos, Livia Silva Araújo, Magalhães, Luísa Mourão Dias, Soares, Rodrigo Pinto, Marques, Alexandre F., Alves, Marina Luiza Rodrigues, Giunchetti, Rodolfo Cordeiro, Nunes, Maria do Carmo Pereira, Gollob, Kenneth J., Dutra, Walderez Ornelas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328447/
https://ncbi.nlm.nih.gov/pubmed/30662439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03015
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