Activation of Human CD11b(+) B1 B-Cells by Trypanosoma cruzi-Derived Proteins Is Associated With Protective Immune Response in Human Chagas Disease

B-cells mediate humoral adaptive immune response via the production of antibodies and cytokines, and by inducing T-cell activation. These functions can be attributed to distinct B-cell subpopulations. Infection with Trypanosoma cruzi, the causative agent of Chagas disease, induces a polyclonal B-cel...

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Udgivet i:Front Immunol
Main Authors: Passos, Livia Silva Araújo, Magalhães, Luísa Mourão Dias, Soares, Rodrigo Pinto, Marques, Alexandre F., Alves, Marina Luiza Rodrigues, Giunchetti, Rodolfo Cordeiro, Nunes, Maria do Carmo Pereira, Gollob, Kenneth J., Dutra, Walderez Ornelas
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328447/
https://ncbi.nlm.nih.gov/pubmed/30662439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03015
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