HEXOKINASE 2 AS A NOVEL SELECTIVE METABOLIC TARGET FOR RHEUMATOID ARTHRITIS

OBJECTIVES: Recent studies indicate that glucose metabolism is altered in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS). Hexokinases (HK)s catalyze the first step in glucose metabolism and HK2 constitutes the principal HK inducible isoform. We hypothesize that HK2 contributes to the s...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Bustamante, Marta F., Oliveira, Patricia G., Garcia-Carbonell, Ricard, Croft, Adam P, Smith, Jeff M, Serrano, Ramon L., Sanchez-Lopez, Elsa, Liu, Xiao, Kisseleva, Tatiana, Hay, Nissim, Buckley, Christopher D, Firestein, Gary S, Murphy, Anne N, Miyamoto, Shigeki, Guma, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328432/
https://ncbi.nlm.nih.gov/pubmed/30061164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-213103
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