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Choline kinase inhibition in rheumatoid arthritis
OBJECTIVES: Little is known about targeting the metabolome in non-cancer conditions. Choline kinase (ChoKα), an essential enzyme for phosphatidylcholine biosynthesis, is required for cell proliferation and has been implicated in cancer invasiveness. Aggressive behaviour of fibroblast-like synoviocyt...
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| Veröffentlicht in: | Ann Rheum Dis |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382461/ https://ncbi.nlm.nih.gov/pubmed/25274633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-205696 |
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