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Genome Engineering Approaches to Improve Nosokomycin A Production by Streptomyces ghanaensis B38.3

Here we describe our efforts to improve the levels of phosphoglycolipid antibiotic nosokomycin A production by Streptomyces ghanaensis ATCC14672 via genome engineering approaches. Introduction of two extra copies of leucyl tRNA (UUA) gene bldA and one copy of moenomycin biosynthesis gene cluster led...

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Dettagli Bibliografici
Pubblicato in:Indian J Microbiol
Autori principali: Kuzhyk, Yuriy, Lopatniuk, Maria, Luzhetskyy, Andriy, Fedorenko, Victor, Ostash, Bohdan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer India 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328414/
https://ncbi.nlm.nih.gov/pubmed/30728639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12088-018-0761-x
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