Genome Engineering Approaches to Improve Nosokomycin A Production by Streptomyces ghanaensis B38.3

Here we describe our efforts to improve the levels of phosphoglycolipid antibiotic nosokomycin A production by Streptomyces ghanaensis ATCC14672 via genome engineering approaches. Introduction of two extra copies of leucyl tRNA (UUA) gene bldA and one copy of moenomycin biosynthesis gene cluster led...

Full description

Saved in:
Bibliographic Details
Published in:Indian J Microbiol
Main Authors: Kuzhyk, Yuriy, Lopatniuk, Maria, Luzhetskyy, Andriy, Fedorenko, Victor, Ostash, Bohdan
Format: Artigo
Language:Inglês
Published: Springer India 2018
Subjects:
Short Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328414/
https://ncbi.nlm.nih.gov/pubmed/30728639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12088-018-0761-x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items