Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility

Physical changes in skin are among the most visible signs of aging. We found that young dermal fibroblasts secrete high levels of extracellular matrix (ECM) constituents, including proteoglycans, glycoproteins and cartilage-linking proteins. The most abundantly secreted was HAPLN1, a hyaluronic and...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Kaur, Amanpreet, Ecker, Brett L., Douglass, Stephen M., Kugel, Curtis H., Webster, Marie R., Almeida, Filipe V., Somasundaram, Rajasekharan, Hayden, James, Ban, Ehsan, Ahmadzadeh, Hossein, Franco-Barraza, Janusz, Shah, Neelima, Mellis, Ian A., Keeney, Frederick, Kossenkov, Andrew, Tang, Hsin-Yao, Yin, Xiangfan, Liu, Qin, Xu, Xiaowei, Fane, Mitchell, Brafford, Patricia, Herlyn, Meenhard, Speicher, David W., Wargo, Jennifer A., Tetzlaff, Michael T., Haydu, Lauren E., Raj, Arjun, Shenoy, Vivek, Cukierman, Edna, Weeraratna, Ashani T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328333/
https://ncbi.nlm.nih.gov/pubmed/30279173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-0193
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados