Site-specific HNK-1 epitope on alternatively spliced fibronectin type-III repeats in tenascin-C promotes neurite outgrowth of hippocampal neurons through contactin-1

The human natural killer-1 (HNK-1) carbohydrate epitope, composed of a unique sulfated trisaccharide (HSO(3)–3GlcAβ1–3Galβ1–4GlcNAc-R), is highly expressed during brain development and regulates higher brain function. However, it remains unclear which glycoprotein carries the HNK-1 epitope in the em...

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Bibliographic Details
Published in:PLoS One
Main Authors: Nakamura, Ayasa, Morise, Jyoji, Yabuno-Nakagawa, Keiko, Hashimoto, Yuki, Takematsu, Hiromu, Oka, Shogo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328190/
https://ncbi.nlm.nih.gov/pubmed/30629639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210193
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