A Sulfated Glycosaminoglycan Linkage Region Is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets

Human natural killer-1 (HNK-1) carbohydrate (HSO(3)-3GlcAβ1-3Galβ1-4GlcNAc-R) is highly expressed in the brain and required for learning and neural plasticity. We previously demonstrated that expression of the HNK-1 epitope is mostly abolished in knockout mice for GlcAT-P (B3gat1), a major glucurony...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Yabuno, Keiko, Morise, Jyoji, Kizuka, Yasuhiko, Hashii, Noritaka, Kawasaki, Nana, Takahashi, Satoru, Miyata, Shinji, Izumikawa, Tomomi, Kitagawa, Hiroshi, Takematsu, Hiromu, Oka, Shogo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686076/
https://ncbi.nlm.nih.gov/pubmed/26659409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144560
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