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Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cells

Melatonin has protective roles in normal cells and cytotoxic actions in cancer cells, with effects involving autophagy and nuclear factor (erythroid-derived 2)-like 2 (Nrf2) transcription factor pathways. Hypoxia/reoxygenation (H/R) induces oxidative damage and apoptosis. These consequences activate...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sagrillo-Fagundes, Lucas, Bienvenue-Pariseault, Josianne, Vaillancourt, Cathy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328125/
https://ncbi.nlm.nih.gov/pubmed/30629581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202458
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