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Enhancement of himastatin bioproduction via inactivation of atypical repressors in Streptomyces hygroscopicus

Three atypical regulatory genes, hmtABD have been discovered within the himastatin biosynthetic gene cluster (BGC) in Streptomyces hygroscopicus ATCC 53653 and the roles of their products have been identified. HmtA and HmtD do not show any structurally distinct features characteristic of regulatory...

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Détails bibliographiques
Publié dans:Metab Eng Commun
Auteurs principaux: Xie, Yunchang, Li, Qinglian, Qin, Xiangjing, Ju, Jianhua, Ma, Junying
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328088/
https://ncbi.nlm.nih.gov/pubmed/30671346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mec.2018.e00084
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