Genome Sequencing of Streptomyces olivaceus SCSIO T05 and Activated Production of Lobophorin CR4 via Metabolic Engineering and Genome Mining

Marine-sourced actinomycete genus Streptomyces continues to be an important source of new natural products. Here we report the complete genome sequence of deep-sea-derived Streptomyces olivaceus SCSIO T05, harboring 37 putative biosynthetic gene clusters (BGCs). A cryptic BGC for type I polyketides...

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發表在:Mar Drugs
Main Authors: Zhang, Chunyan, Ding, Wenjuan, Qin, Xiangjing, Ju, Jianhua
格式: Artigo
語言:Inglês
出版: MDPI 2019
主題:
Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835275/
https://ncbi.nlm.nih.gov/pubmed/31635159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17100593
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