Enriched Cd141(+) DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis

CD141(+) DC are implicated in antiviral and antitumor immunity. However, mechanistic studies in autoimmune disease are limited. This is the first study to our knowledge examining CD141(+) DC in autoimmune disease, specifically inflammatory arthritis (IA). We identified significant enrichment of CD14...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Canavan, Mary, Walsh, Alice M., Bhargava, Vipul, Wade, Sarah M., McGarry, Trudy, Marzaioli, Viviana, Moran, Barry, Biniecka, Monika, Convery, Hannah, Wade, Siobhan, Orr, Carl, Mullan, Ronan, Fletcher, Jean M., Nagpal, Sunil, Veale, Douglas J., Fearon, Ursula
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6328029/
https://ncbi.nlm.nih.gov/pubmed/30518680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95228
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