Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis

During inflammation, immune cells activated by toll-like receptors (TLRs) have the ability to undergo a bioenergetic switch towards glycolysis in a manner similar to that observed in tumour cells. While TLRs have been implicated in the pathogenesis of rheumatoid arthritis (RA), their role in regulat...

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Veröffentlicht in:Sci Rep
Hauptverfasser: McGarry, Trudy, Biniecka, Monika, Gao, Wei, Cluxton, Deborah, Canavan, Mary, Wade, Siobhan, Wade, Sarah, Gallagher, Lorna, Orr, Carl, Veale, Douglas J., Fearon, Ursula
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320554/
https://ncbi.nlm.nih.gov/pubmed/28225071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43165
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