טוען...
Treatment of established TH2 cells with 4μ8c, an inhibitor of IRE1α, blocks IL-5 but not IL-4 secretion
BACKGROUND: T cell activation induces ER stress and upregulates Inositol Requiring Enzyme 1 alpha (IRE1α), an activator of the unfolded protein response (UPR) pathway. Inhibition of IRE1α RNase activity in activated CD4(+) splenocytes from naïve mice, via treatment of the cells with the commercially...
שמור ב:
| הוצא לאור ב: | BMC Immunol |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6327572/ https://ncbi.nlm.nih.gov/pubmed/30630412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-018-0283-7 |
| תגים: |
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