DynamicME: dynamic simulation and refinement of integrated models of metabolism and protein expression

BACKGROUND: Genome-scale models of metabolism and macromolecular expression (ME models) enable systems-level computation of proteome allocation coupled to metabolic phenotype. RESULTS: We develop DynamicME, an algorithm enabling time-course simulation of cell metabolism and protein expression. Dynam...

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Bibliographic Details
Published in:BMC Syst Biol
Main Authors: Yang, Laurence, Ebrahim, Ali, Lloyd, Colton J., Saunders, Michael A., Palsson, Bernhard O.
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327497/
https://ncbi.nlm.nih.gov/pubmed/30626386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-018-0675-6
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