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Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost

BACKGROUND: Methotrexate is an important component in many chemotherapy protocols. The blood concentration of Methotrexate is used to determine the regimen of folinic acid. However, the lower limit of Siemens assay kit is 0.30 μmol/L in China. This study extended the limit from 0.3 to 0.05 μmol/L an...

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Dettagli Bibliografici
Pubblicato in:BMC Pharmacol Toxicol
Autori principali: Shi, Xiaoping, Gao, Hui, Li, Zhong, Li, Jinghua, Liu, Yang, Li, Lujuan, Zhang, Qi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327437/
https://ncbi.nlm.nih.gov/pubmed/30626430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0283-5
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