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Modified enzyme multiplied immunoassay technique of methotrexate assay to improve sensitivity and reduce cost

BACKGROUND: Methotrexate is an important component in many chemotherapy protocols. The blood concentration of Methotrexate is used to determine the regimen of folinic acid. However, the lower limit of Siemens assay kit is 0.30 μmol/L in China. This study extended the limit from 0.3 to 0.05 μmol/L an...

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Detalhes bibliográficos
Publicado no:BMC Pharmacol Toxicol
Main Authors: Shi, Xiaoping, Gao, Hui, Li, Zhong, Li, Jinghua, Liu, Yang, Li, Lujuan, Zhang, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327437/
https://ncbi.nlm.nih.gov/pubmed/30626430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0283-5
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