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Buformin increases radiosensitivity in cervical cancer cells via cell-cycle arrest and delayed DNA-damage repair

Buformin is a commonly used hypoglycemic agent, and numerous studies have shown that buformin has potent antitumor effects in several malignancies. In this study, we aimed to assess the cytotoxic effect of buformin combined with ionizing radiation (IR) on two human cervical cancer cell lines (Hela a...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Chen, Ling, Zhang, Ting, Liu, Qiuli, Tang, Mei, Yang, Yu’e, Wang, Yuan, Qiu, Haifeng, Yu, Jinjin
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327368/
https://ncbi.nlm.nih.gov/pubmed/32459508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370218813320
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