Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

The increase in cellular radiosensitivity by EGF receptor (EGFR) inhibition has been shown to be attributable to the induction of a G1-arrest in p53-proficient cells. Because EGFR targeting in combination with radiotherapy is used to treat head and neck squamous cell carcinomas (HNSCC) which are pre...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Kriegs, Malte, Kasten-Pisula, Ulla, Riepen, Britta, Hoffer, Konstantin, Struve, Nina, Myllynen, Laura, Braig, Friederike, Binder, Mascha, Rieckmann, Thorsten, Grénman, Reidar, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216710/
https://ncbi.nlm.nih.gov/pubmed/27281611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9161
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