Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

The increase in cellular radiosensitivity by EGF receptor (EGFR) inhibition has been shown to be attributable to the induction of a G1-arrest in p53-proficient cells. Because EGFR targeting in combination with radiotherapy is used to treat head and neck squamous cell carcinomas (HNSCC) which are pre...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kriegs, Malte, Kasten-Pisula, Ulla, Riepen, Britta, Hoffer, Konstantin, Struve, Nina, Myllynen, Laura, Braig, Friederike, Binder, Mascha, Rieckmann, Thorsten, Grénman, Reidar, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216710/
https://ncbi.nlm.nih.gov/pubmed/27281611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9161
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