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Oleanolic Acid Ameliorates Aβ(25-35) Injection-induced Memory Deficit in Alzheimer’s Disease Model Rats by Maintaining Synaptic Plasticity

BACKGROUND: Abnormal amyloid β (Aβ) accumulation and deposition in the hippocampus is an essential process in Alzheimer’s disease (AD). OBJECTIVE: To investigate whether Oleanolic acid (OA) could improve memory deficit in AD model and its possible mechanism. METHODS: Forty-five SD rats were randomly...

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Библиографические подробности
Опубликовано в: :CNS Neurol Disord Drug Targets
Главные авторы: Wang, Kai, Sun, Weiming, Zhang, Linlin, Guo, Wei, Xu, Jiachun, Liu, Shuang, Zhou, Zhen, Zhang, Yulian
Формат: Artigo
Язык:Inglês
Опубликовано: Bentham Science Publishers 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327117/
https://ncbi.nlm.nih.gov/pubmed/29793416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1871527317666180525113109
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