Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche

In many tissues, homeostasis is maintained by physical contact between stem cells and an anatomically defined niche. However, how stem cell homeostasis is achieved in environments where cells are motile and dispersed among their progeny remains unknown. Using murine spermatogenesis as a model, we fi...

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Veröffentlicht in:Cell Stem Cell
Hauptverfasser: Kitadate, Yu, Jörg, David J., Tokue, Moe, Maruyama, Ayumi, Ichikawa, Rie, Tsuchiya, Soken, Segi-Nishida, Eri, Nakagawa, Toshinori, Uchida, Aya, Kimura-Yoshida, Chiharu, Mizuno, Seiya, Sugiyama, Fumihiro, Azami, Takuya, Ema, Masatsugu, Noda, Chiyo, Kobayashi, Satoru, Matsuo, Isao, Kanai, Yoshiakira, Nagasawa, Takashi, Sugimoto, Yukihiko, Takahashi, Satoru, Simons, Benjamin D., Yoshida, Shosei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6327111/
https://ncbi.nlm.nih.gov/pubmed/30581080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.11.013
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